|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:HSP27
|
|
gptkbp:associatedWith
|
Charcot-Marie-Tooth disease, type 2F
Distal hereditary motor neuropathy, type II
|
|
gptkbp:biologicalProcess
|
protein folding
chaperone binding
response to heat
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:Entrez_Gene_ID
|
ENSP00000261701
GC07P076285
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:function
|
prevents aggregation of denatured proteins
acts as a molecular chaperone
|
|
gptkbp:gene
|
gptkb:HSPB1
|
|
gptkbp:HGNC_ID
|
5246
|
|
gptkbp:InterPro
|
IPR002068
|
|
gptkbp:KEGGID
|
hsa:3315
|
|
gptkbp:last_sequence_update
|
2007-10-23
|
|
gptkbp:lastAnnotationUpdate
|
2022-02-23
|
|
gptkbp:length
|
205
|
|
gptkbp:locatedOnChromosome
|
7
|
|
gptkbp:molecularWeight
|
22782
|
|
gptkbp:OMIM
|
602195
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
P14602
P42930
|
|
gptkbp:PDB
|
4MJH
2N3J
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:protein_name
|
gptkb:Heat_shock_protein_beta-1
|
|
gptkbp:proteinFamily
|
PF00011
|
|
gptkbp:RefSeq
|
NP_001531.1
|
|
gptkbp:reviewed_in_UniProt
|
yes
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:sequenceVersion
|
4
|
|
gptkbp:structure
|
forms homodimers and oligomers
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:tissue_specificity
|
high in heart
high in brain
high in skeletal muscle
|
|
gptkbp:UniGene
|
Hs.654
|
|
gptkbp:UniProtID
|
gptkb:P02545
|
|
gptkbp:bfsParent
|
gptkb:LMNA
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P02545
|