Organic cation transporter 2
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
ABC transporter |
| gptkbp:alternativeName |
gptkb:OCT2
gptkb:SLC22A2 |
| gptkbp:encodedBy |
gptkb:SLC22A2_gene
|
| gptkbp:expressedIn |
proximal tubule
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
mediates uptake of organic cations from blood into renal tubular cells
|
| https://www.w3.org/2000/01/rdf-schema#label |
Organic cation transporter 2
|
| gptkbp:locatedIn |
gptkb:kidney
brain liver |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_6
|
| gptkbp:memberOf |
gptkb:solute_carrier_family
|
| gptkbp:regulates |
regulated by transcription factors
|
| gptkbp:significance |
genetic variants affect drug response
involved in drug-drug interactions |
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:structure |
12 transmembrane domains
|
| gptkbp:transportation |
gptkb:metformin
drugs organic cations creatinine |
| gptkbp:UniProtID |
O15244
|
| gptkbp:bfsParent |
gptkb:OCT2
|
| gptkbp:bfsLayer |
6
|