Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
SLC22A8 protein
|
| gptkbp:associatedWith |
altered drug clearance
renal drug toxicity |
| gptkbp:encodedBy |
SLC22A8
|
| gptkbp:fullName |
Organic Anion Transporter 3
|
| gptkbp:function |
transports organic anions
renal drug excretion |
| gptkbp:gene |
SLC22A8
|
| gptkbp:HGNC_ID |
10967
|
| https://www.w3.org/2000/01/rdf-schema#label |
OAT3
|
| gptkbp:inhibitedBy |
gptkb:probenecid
cimetidine |
| gptkbp:locatedOnChromosome |
11q12.3
|
| gptkbp:location |
gptkb:kidney
basolateral membrane of renal proximal tubule |
| gptkbp:memberOf |
gptkb:solute_carrier_family
|
| gptkbp:OMIM |
604842
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:substrate |
gptkb:antibiotic
gptkb:methotrexate nonsteroidal anti-inflammatory drugs furosemide para-aminohippurate |
| gptkbp:UniProtID |
Q9UNQ4
|
| gptkbp:bfsParent |
gptkb:solute_carrier_family_22
|
| gptkbp:bfsLayer |
7
|