Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:Delta_ligand
gptkb:Jagged_ligand |
| gptkbp:cleavage |
gptkb:gamma-secretase
|
| gptkbp:component |
gptkb:Notch_signaling_pathway
|
| gptkbp:discoveredIn |
gptkb:Drosophila_melanogaster
|
| gptkbp:domain |
EGF-like repeats
ankyrin repeats |
| gptkbp:encodedBy |
gptkb:NOTCH3_gene
gptkb:NOTCH1_gene gptkb:NOTCH2_gene gptkb:NOTCH4_gene |
| gptkbp:foundIn |
animals
|
| gptkbp:function |
cell signaling
developmental processes regulation of cell fate |
| https://www.w3.org/2000/01/rdf-schema#label |
Notch protein
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:CADASIL gptkb:Alagille_syndrome |
| gptkbp:orthologIn |
gptkb:C._elegans
gptkb:zebrafish humans mice |
| gptkbp:role |
angiogenesis
neurogenesis stem cell maintenance hematopoiesis |
| gptkbp:structure |
single-pass transmembrane protein
|
| gptkbp:symbol |
gptkb:NOTCH
|
| gptkbp:bfsParent |
gptkb:Notch_gene
|
| gptkbp:bfsLayer |
6
|