Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
signaling molecule |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:binds |
gptkb:Notch_receptor
|
| gptkbp:domain |
EGF-like repeats
DSL domain |
| gptkbp:encodedBy |
gptkb:JAG1_gene
JAG2 gene |
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
gptkb:Notch_signaling_pathway
|
| https://www.w3.org/2000/01/rdf-schema#label |
Jagged ligand
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:mutationAssociatedWith |
gptkb:Alagille_syndrome
|
| gptkbp:orthologIn |
Drosophila (as Serrate)
|
| gptkbp:postTranslationalModification |
glycosylation
ubiquitination |
| gptkbp:regulates |
cell differentiation
cell proliferation |
| gptkbp:role |
embryonic development
cell fate determination tissue homeostasis |
| gptkbp:structure |
single-pass transmembrane protein
|
| gptkbp:bfsParent |
gptkb:Notch_protein
gptkb:Notch_signaling_pathway |
| gptkbp:bfsLayer |
7
|