Nonsteroidal Anti-Inflammatory Drugs
GPTKB entity
Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:abbreviation |
gptkb:NSAIDs
|
| gptkbp:category |
analgesic
anti-inflammatory antipyretic |
| gptkbp:contraindication |
gptkb:peptic_ulcer_disease
chronic kidney disease aspirin allergy |
| gptkbp:discoveredIn |
20th century
|
| gptkbp:example |
gptkb:diclofenac
gptkb:ibuprofen gptkb:naproxen gptkb:aspirin gptkb:celecoxib indomethacin ketoprofen meloxicam |
| https://www.w3.org/2000/01/rdf-schema#label |
Nonsteroidal Anti-Inflammatory Drugs
|
| gptkbp:introducedIn |
gptkb:aspirin
|
| gptkbp:mechanismOfAction |
inhibit cyclooxygenase enzymes
reduce prostaglandin synthesis |
| gptkbp:notEffectiveAgainst |
viral infections
bacterial infections |
| gptkbp:notOpioid |
true
|
| gptkbp:notSteroid |
true
|
| gptkbp:OTC |
gptkb:ibuprofen
gptkb:naproxen gptkb:aspirin |
| gptkbp:prescriptionRequired |
gptkb:diclofenac
gptkb:celecoxib indomethacin |
| gptkbp:riskFactor |
hypertension
gastrointestinal bleeding cardiovascular events renal toxicity |
| gptkbp:routeOfAdministration |
oral
topical intravenous |
| gptkbp:sideEffect |
renal impairment
ulcer increased bleeding risk gastrointestinal irritation |
| gptkbp:usedFor |
pain relief
fever reduction inflammation reduction |
| gptkbp:usedIn |
osteoarthritis
headache rheumatoid arthritis musculoskeletal pain menstrual pain |
| gptkbp:bfsParent |
gptkb:Systemic_Drug_Reaction
|
| gptkbp:bfsLayer |
7
|