Nonsteroidal Anti-Inflammatory Drugs

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:drug
gptkbp:abbreviation	gptkb:NSAIDs
gptkbp:category	gptkb:analgesic gptkb:antipyretic anti-inflammatory
gptkbp:contraindication	gptkb:peptic_ulcer_disease chronic kidney disease aspirin allergy
gptkbp:discoveredIn	20th century
gptkbp:example	gptkb:diclofenac gptkb:ibuprofen gptkb:naproxen gptkb:aspirin gptkb:celecoxib indomethacin ketoprofen meloxicam
gptkbp:introducedIn	gptkb:aspirin
gptkbp:mechanismOfAction	inhibit cyclooxygenase enzymes reduce prostaglandin synthesis
gptkbp:notEffectiveAgainst	viral infections bacterial infections
gptkbp:notOpioid	true
gptkbp:notSteroid	true
gptkbp:OTC	gptkb:ibuprofen gptkb:naproxen gptkb:aspirin
gptkbp:prescriptionRequired	gptkb:diclofenac gptkb:celecoxib indomethacin
gptkbp:riskFactor	hypertension gastrointestinal bleeding cardiovascular events renal toxicity
gptkbp:routeOfAdministration	oral topical intravenous
gptkbp:sideEffect	renal impairment ulcer increased bleeding risk gastrointestinal irritation
gptkbp:usedFor	pain relief fever reduction inflammation reduction
gptkbp:usedIn	osteoarthritis headache rheumatoid arthritis musculoskeletal pain menstrual pain
gptkbp:bfsParent	gptkb:Systemic_Drug_Reaction
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Nonsteroidal Anti-Inflammatory Drugs