Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
Cripto
|
| gptkbp:encodedBy |
NODAL gene
|
| gptkbp:enemyOf |
gptkb:Lefty
gptkb:Cerberus DAN family proteins |
| gptkbp:expressedIn |
early embryogenesis
|
| gptkbp:family |
gptkb:TGF-beta_superfamily
|
| gptkbp:foundIn |
vertebrates
|
| gptkbp:function |
embryonic development
endoderm formation mesoderm formation left-right axis specification |
| gptkbp:location |
extracellular space
|
| gptkbp:molecularWeight |
~45 kDa
|
| gptkbp:orthologIn |
zebrafish cyclops
zebrafish squint |
| gptkbp:pathway |
Nodal signaling pathway
|
| gptkbp:postTranslationalModification |
cleavage
glycosylation |
| gptkbp:recipient |
gptkb:ActRIIB
gptkb:ALK4 |
| gptkbp:regulates |
Smad2/3 phosphorylation
gene expression during gastrulation |
| gptkbp:role |
gptkb:cancer
gptkb:holoprosencephaly congenital heart defects |
| gptkbp:structure |
dimer
|
| gptkbp:bfsParent |
gptkb:Nodal_gene
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
Nodal protein
|