Nodal protein

GPTKB entity

Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy Cripto
gptkbp:encodedBy NODAL gene
gptkbp:enemyOf gptkb:Lefty
gptkb:Cerberus
DAN family proteins
gptkbp:expressedIn early embryogenesis
gptkbp:family gptkb:TGF-beta_superfamily
gptkbp:foundIn vertebrates
gptkbp:function embryonic development
endoderm formation
mesoderm formation
left-right axis specification
gptkbp:location extracellular space
gptkbp:molecularWeight ~45 kDa
gptkbp:orthologIn zebrafish cyclops
zebrafish squint
gptkbp:pathway Nodal signaling pathway
gptkbp:postTranslationalModification cleavage
glycosylation
gptkbp:recipient gptkb:ActRIIB
gptkb:ALK4
gptkbp:regulates Smad2/3 phosphorylation
gene expression during gastrulation
gptkbp:role gptkb:cancer
gptkb:holoprosencephaly
congenital heart defects
gptkbp:structure dimer
gptkbp:bfsParent gptkb:Nodal_gene
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label Nodal protein