|
gptkbp:instanceOf
|
gptkb:neurodegenerative_disease
|
|
gptkbp:affects
|
frontal lobes
temporal lobes
|
|
gptkbp:alsoKnownAs
|
gptkb:FTD
|
|
gptkbp:cause
|
genetic mutations
abnormal protein accumulation
|
|
gptkbp:complication
|
gptkb:death
loss of independence
|
|
gptkbp:diagnosedBy
|
gptkb:neurological_examination
brain imaging
neuropsychological testing
|
|
gptkbp:differentialDiagnosis
|
gptkb:Alzheimer's_disease
psychiatric disorders
|
|
gptkbp:firstDescribed
|
gptkb:Arnold_Pick
1892
|
|
gptkbp:ICD-10_code
|
G31.0
|
|
gptkbp:MeSH_ID
|
D020961
|
|
gptkbp:mortalityRate
|
high
|
|
gptkbp:OMIM
|
600274
|
|
gptkbp:onset
|
typically before age 65
|
|
gptkbp:prevalence
|
second most common early-onset dementia
|
|
gptkbp:prognosis
|
progressive
incurable
|
|
gptkbp:progression
|
gradual
|
|
gptkbp:relatedTo
|
gptkb:Pick's_disease
|
|
gptkbp:riskFactor
|
family history
genetic mutations in C9orf72 gene
genetic mutations in GRN gene
genetic mutations in MAPT gene
|
|
gptkbp:subspecies
|
gptkb:behavioral_variant_FTD
gptkb:primary_progressive_aphasia
gptkb:semantic_dementia
|
|
gptkbp:symptom
|
behavioral changes
personality changes
impaired executive function
language difficulties
|
|
gptkbp:treatment
|
supportive care
symptom management
|
|
gptkbp:bfsParent
|
gptkb:Walter_Bruce_Willis
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Frontotemporal dementia
|