Statements (42)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
neurodegenerative disease
|
| gptkbp:affects |
frontal lobes
temporal lobes |
| gptkbp:alsoKnownAs |
gptkb:FTD
|
| gptkbp:cause |
genetic mutations
abnormal protein accumulation |
| gptkbp:complication |
death
loss of independence |
| gptkbp:diagnosedBy |
brain imaging
neurological examination neuropsychological testing |
| gptkbp:differentialDiagnosis |
gptkb:Alzheimer's_disease
psychiatric disorders |
| gptkbp:firstDescribed |
gptkb:Arnold_Pick
1892 |
| https://www.w3.org/2000/01/rdf-schema#label |
Frontotemporal dementia
|
| gptkbp:ICD-10_code |
G31.0
|
| gptkbp:MeSH_ID |
D020961
|
| gptkbp:mortalityRate |
high
|
| gptkbp:OMIM |
600274
|
| gptkbp:onset |
typically before age 65
|
| gptkbp:prevalence |
second most common early-onset dementia
|
| gptkbp:prognosis |
progressive
incurable |
| gptkbp:progression |
gradual
|
| gptkbp:relatedTo |
gptkb:Pick's_disease
|
| gptkbp:riskFactor |
family history
genetic mutations in C9orf72 gene genetic mutations in GRN gene genetic mutations in MAPT gene |
| gptkbp:subspecies |
gptkb:behavioral_variant_FTD
gptkb:primary_progressive_aphasia gptkb:semantic_dementia |
| gptkbp:symptom |
behavioral changes
personality changes impaired executive function language difficulties |
| gptkbp:treatment |
supportive care
symptom management |
| gptkbp:bfsParent |
gptkb:dementia
gptkb:Walter_Bruce_Willis |
| gptkbp:bfsLayer |
5
|