Statements (60)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:neurodegenerative_diseases
|
gptkbp:affects |
gptkb:language
quality of life behavior social skills decision-making abilities |
gptkbp:can_cause |
apathy
compulsive behavior emotional blunting disinhibition |
gptkbp:can_lead_to |
social withdrawal
increased caregiver burden loss of independence caregiver stress loss of empathy increased impulsivity |
gptkbp:can_result_in |
financial difficulties
loss of job |
gptkbp:cause |
early-onset dementia
|
gptkbp:caused_by |
abnormal protein accumulation
|
gptkbp:descendant |
gptkb:true
|
gptkbp:diagnosis |
clinical assessment
neuroimaging |
gptkbp:evaluates |
neuropsychological testing
|
gptkbp:has_a_focus_on |
neurological research
aging research |
https://www.w3.org/2000/01/rdf-schema#label |
Frontotemporal dementia
|
gptkbp:impact |
family dynamics
|
gptkbp:is_a_subject_of |
clinical trials
patient advocacy |
gptkbp:is_associated_with |
genetic mutations
TDP-43 protein abnormalities tau protein abnormalities changes in eating habits |
gptkbp:is_characterized_by |
loss of insight
progressive degeneration of the frontal and temporal lobes |
gptkbp:is_common_in |
people aged 40 to 65
|
gptkbp:is_different_from |
gptkb:neurodegenerative_diseases
|
gptkbp:is_linked_to |
neuroinflammation
|
gptkbp:is_often_accompanied_by |
other neurological symptoms
|
gptkbp:is_often_discussed_in |
gptkb:literature
|
gptkbp:is_often_seen_in |
normal aging
|
gptkbp:is_often_underdiagnosed |
gptkb:true
|
gptkbp:is_part_of |
the spectrum of neurodegenerative diseases
|
gptkbp:is_recognized_as |
a significant public health issue
|
gptkbp:is_recognized_by |
gptkb:the_World_Health_Organization
mental health disorders other types of dementia |
gptkbp:known_as |
gptkb:Pick's_disease
|
gptkbp:research_is_ongoing_for |
effective treatments
better diagnostic methods |
gptkbp:scientific_classification |
behavioral variant frontotemporal dementia
primary progressive aphasia |
gptkbp:symptoms |
changes in personality
difficulty with speech |
gptkbp:treatment |
supportive care
medications for symptoms |
gptkbp:type_of |
frontotemporal lobar degeneration
|
gptkbp:bfsParent |
gptkb:FUS_mutations
|
gptkbp:bfsLayer |
5
|