Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
calcium signaling
calcineurin |
| gptkbp:discoveredBy |
Anjana Rao
|
| gptkbp:DNA_binding_domain |
Rel homology domain
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
gptkb:B_cells gptkb:T_cells cardiac muscle neurons |
| gptkbp:fullName |
Nuclear Factor of Activated T-cells
|
| gptkbp:function |
transcription regulation
immune response regulation T-cell activation |
| gptkbp:gene |
gptkb:NFATC2
NFATC4 NFAT5 NFATC1 NFATC3 |
| https://www.w3.org/2000/01/rdf-schema#label |
NFAT transcription factors
|
| gptkbp:inhibitedBy |
gptkb:tacrolimus
cyclosporin A |
| gptkbp:member |
NFATc3
NFATc4 NFAT5 NFATc1 NFATc2 |
| gptkbp:orthologIn |
gptkb:human
gptkb:mouse right |
| gptkbp:phosphorylationState |
dephosphorylated (active)
phosphorylated (inactive) |
| gptkbp:regulates |
apoptosis
cell differentiation angiogenesis neuronal development developmental processes muscle fiber type specification immune cell development osteoclast differentiation IL-2 gene expression cytokine gene expression |
| gptkbp:relatedTo |
gptkb:cancer
autoimmune diseases inflammation cardiac hypertrophy |
| gptkbp:subcellularLocation |
cytoplasm (inactive)
nucleus (active) |
| gptkbp:bfsParent |
gptkb:DYRK1A
|
| gptkbp:bfsLayer |
7
|