NAD-dependent deacetylase sirtuin-6
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:SIRT6
SIR2-like protein 6 |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:diabetes aging |
| gptkbp:cofactor |
NAD+
|
| gptkbp:encodedBy |
gptkb:SIRT6_gene
|
| gptkbp:family |
sirtuin family
|
| gptkbp:function |
histone deacetylase
ADP-ribosyltransferase |
| gptkbp:gene |
gptkb:SIRT6
|
| https://www.w3.org/2000/01/rdf-schema#label |
NAD-dependent deacetylase sirtuin-6
|
| gptkbp:involvedIn |
DNA repair
genomic stability metabolic regulation |
| gptkbp:locatedOnChromosome |
gptkb:19p13.3
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:molecularWeight |
39 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:PDB |
3K35
|
| gptkbp:regulates |
glucose homeostasis
telomere maintenance NF-kappaB signaling |
| gptkbp:UniProtID |
gptkb:Q8N6T7
|
| gptkbp:bfsParent |
gptkb:SIRT6
|
| gptkbp:bfsLayer |
8
|