Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:SIR2L6
SIR2-like protein 6 |
| gptkbp:associatedWith |
gptkb:cancer
longevity metabolic diseases genomic stability |
| gptkbp:encodes |
Sirtuin 6 protein
|
| gptkbp:Entrez_Gene_ID |
51548
ENSG00000129484 |
| gptkbp:expressedIn |
various human tissues
|
| gptkbp:function |
regulation of metabolism
histone deacetylase activity regulation of inflammation regulation of DNA repair regulation of aging |
| gptkbp:HGNC_ID |
gptkb:HGNC:14934
|
| https://www.w3.org/2000/01/rdf-schema#label |
SIRT6 gene
|
| gptkbp:locatedOnChromosome |
gptkb:19p13.3
gptkb:chromosome_19 |
| gptkbp:memberOf |
sirtuin family
|
| gptkbp:OMIM |
606211
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Sirt6
|
| gptkbp:product |
gptkb:NAD-dependent_deacetylase
|
| gptkbp:regulates |
glucose homeostasis
DNA double-strand break repair telomere maintenance NF-kB signaling |
| gptkbp:UniProtID |
gptkb:Q8N6T7
|
| gptkbp:bfsParent |
gptkb:SIRT6
|
| gptkbp:bfsLayer |
8
|