Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alternativeName |
gptkb:SOD2
gptkb:Mitochondrial_superoxide_dismutase |
gptkbp:cofactor |
manganese
|
gptkbp:discoveredBy |
1969
|
gptkbp:EC_number |
1.15.1.1
|
gptkbp:foundIn |
eukaryotes
some prokaryotes |
gptkbp:fullName |
gptkb:Manganese_superoxide_dismutase
|
gptkbp:function |
catalyzes the dismutation of superoxide radicals to oxygen and hydrogen peroxide
|
gptkbp:gene |
gptkb:SOD2
|
https://www.w3.org/2000/01/rdf-schema#label |
Mn-SOD
|
gptkbp:importantFor |
protects cells from oxidative stress
|
gptkbp:locatedOnChromosome |
gptkb:human_chromosome_6q25
|
gptkbp:location |
mitochondria
|
gptkbp:molecularWeight |
about 96 kDa (tetramer)
|
gptkbp:mutationAssociatedWith |
mutations can cause mitochondrial diseases
|
gptkbp:PDB |
gptkb:1LUV
|
gptkbp:relatedTo |
gptkb:Fe-SOD
gptkb:Cu/Zn-SOD |
gptkbp:structure |
homotetramer in humans
|
gptkbp:UniProtID |
P04179 (human)
|
gptkbp:bfsParent |
gptkb:SOD
gptkb:hsa:6647 |
gptkbp:bfsLayer |
6
|