Mitochondrial Complex I protein

URI: https://gptkb.org/entity/Mitochondrial_Complex_I_protein
GPTKB entity
Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:NADH:ubiquinone_oxidoreductase
gptkbp:catalyzes NADH oxidation
ubiquinone reduction
gptkbp:cofactor gptkb:FMN
iron-sulfur clusters
gptkbp:component electron transport chain
gptkbp:EC_number 1.6.5.3
gptkbp:energyProductionRole ATP synthesis
gptkbp:foundIn gptkb:Bacteria
eukaryotes
gptkbp:function electron transport
proton translocation
gptkbp:gene gptkb:mitochondrial_DNA
nuclear DNA
https://www.w3.org/2000/01/rdf-schema#label Mitochondrial Complex I protein
gptkbp:inhibitedBy gptkb:piericidin_A
gptkb:rotenone
amytal
gptkbp:locatedIn mitochondrial inner membrane
gptkbp:mass ~1 MDa
gptkbp:mutationAssociatedWith gptkb:Parkinson's_disease
gptkb:Leigh_syndrome
mitochondrial complex I deficiency
gptkbp:step mitochondrial respiratory chain
gptkbp:structure L-shaped
gptkbp:subunit gptkb:ND1
gptkb:ND2
gptkb:ND3
gptkb:ND4
gptkb:ND4L
gptkb:ND5
gptkb:ND6
gptkb:NDUFS1
gptkb:NDUFS2
gptkb:NDUFS3
gptkb:NDUFS4
gptkb:NDUFS7
gptkb:NDUFS8
gptkb:NDUFV1
gptkb:NDUFV2
gptkb:NDUFV3
gptkbp:subunitCount at least 45
gptkbp:bfsParent gptkb:MCI_(gene)
gptkbp:bfsLayer 5