|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
immunological disorders
|
|
gptkbp:component
|
nucleosome remodeling and deacetylase complex
|
|
gptkbp:domain
|
Methyl-CpG-binding domain
|
|
gptkbp:encodedBy
|
MBD2 gene
|
|
gptkbp:Entrez_Gene_ID
|
8932
ENSG00000134046
|
|
gptkbp:fullName
|
Methyl-CpG-binding domain protein 2
|
|
gptkbp:function
|
transcriptional repression
binds methylated DNA
methylated DNA binding
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GOProcess
|
regulation of transcription, DNA-templated
|
|
gptkbp:HGNC_ID
|
HGNC:6915
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MBD2
|
|
gptkbp:interactsWith
|
gptkb:NuRD_complex
|
|
gptkbp:locatedOnChromosome
|
chromosome 18q21
|
|
gptkbp:memberOf
|
MBD protein family
|
|
gptkbp:molecularWeight
|
~43 kDa
|
|
gptkbp:OMIM
|
603547
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
1IG4
|
|
gptkbp:RefSeq
|
NM_003927
|
|
gptkbp:relatedTo
|
DNA methylation
epigenetic regulation
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
Q9UBB5
|
|
gptkbp:bfsParent
|
gptkb:NuRD_complex
gptkb:SIN3A
gptkb:MBD_(methyl-CpG-binding_domain)
|
|
gptkbp:bfsLayer
|
8
|