MBD (methyl-CpG-binding domain)

GPTKB entity

Statements (19)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:binds methylated CpG dinucleotides
gptkbp:discoveredIn 1992
gptkbp:foundIn MBD family proteins
gptkbp:function epigenetic regulation
transcriptional repression
gptkbp:GO_term GO:0010385
https://www.w3.org/2000/01/rdf-schema#label MBD (methyl-CpG-binding domain)
gptkbp:InterPro IPR001739
gptkbp:length ~70 amino acids
gptkbp:presentIn gptkb:MBD2
gptkb:MBD3
gptkb:MBD1
MBD4
MeCP2
gptkbp:proteinFamily PF01429
gptkbp:structure alpha/beta fold
gptkbp:bfsParent gptkb:MECP2
gptkbp:bfsLayer 7