Lymphocyte function-associated antigen 1
GPTKB entity
Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:abbreviation |
gptkb:LFA-1
|
gptkbp:associatedWith |
gptkb:leukocyte_adhesion_deficiency
|
gptkbp:binds |
gptkb:ICAM-1
gptkb:ICAM-2 gptkb:ICAM-3 |
gptkbp:composedOf |
gptkb:CD11a
gptkb:CD18 |
gptkbp:discoveredBy |
gptkb:Tim_Springer
|
gptkbp:encodedBy |
gptkb:ITGB2_gene
ITGAL gene |
gptkbp:foundIn |
gptkb:leukocytes
lymphocytes |
gptkbp:function |
cell adhesion
|
gptkbp:heldBy |
integrin
|
https://www.w3.org/2000/01/rdf-schema#label |
Lymphocyte function-associated antigen 1
|
gptkbp:role |
immune response
T cell activation leukocyte migration |
gptkbp:structure |
heterodimer
|
gptkbp:target |
therapeutic antibodies
|
gptkbp:bfsParent |
gptkb:LFA-1
|
gptkbp:bfsLayer |
8
|