Leukemia Inhibitory Factor Receptor
GPTKB entity
Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
gptkbp:abbreviation |
gptkb:LIFR
|
gptkbp:alternativeSplicing |
yes
|
gptkbp:associatedWith |
gptkb:Stüve-Wiedemann_syndrome
|
gptkbp:binds |
gptkb:Leukemia_Inhibitory_Factor
gptkb:Cardiotrophin-1 Ciliary neurotrophic factor Oncostatin M |
gptkbp:discoveredIn |
1992
|
gptkbp:encodedBy |
LIFR gene
|
gptkbp:Entrez_Gene_ID |
3977
|
gptkbp:expressedIn |
various tissues
|
gptkbp:formsComplexWith |
gptkb:gp130
|
gptkbp:function |
cytokine receptor
|
gptkbp:HGNC_ID |
6596
|
https://www.w3.org/2000/01/rdf-schema#label |
Leukemia Inhibitory Factor Receptor
|
gptkbp:involvedIn |
gptkb:JAK/STAT_signaling_pathway
cell differentiation cell proliferation embryonic stem cell self-renewal |
gptkbp:locatedOnChromosome |
gptkb:chromosome_5
|
gptkbp:location |
gptkb:cell_membrane
|
gptkbp:molecularWeight |
~110 kDa
|
gptkbp:OMIM |
151443
|
gptkbp:orthologInMouse |
Lifr
|
gptkbp:UniProtID |
P42702
|
gptkbp:bfsParent |
gptkb:LIFR
|
gptkbp:bfsLayer |
8
|