L-3,4-dihydroxyphenylalanine

GPTKB entity

Predicate	Object
gptkbp:instanceOf	amino acid transporter biochemical compound
gptkbp:absorbedBy	gptkb:small_intestine
gptkbp:approvedBy	gptkb:FDA gptkb:EMA
gptkbp:ATCCode	N04BA01
gptkbp:biosynthesized_from	gptkb:L-tyrosine
gptkbp:CASNumber	59-92-7
gptkbp:commonName	gptkb:L-DOPA
gptkbp:contraindication	nonselective MAO inhibitors
gptkbp:foundIn	gptkb:Mucuna_pruriens gptkb:Vicia_faba animals fungi plants human body
gptkbp:halfLife	0.75–1.5 hours
gptkbp:hasMolecularFormula	C9H11NO4
gptkbp:hasSMILES	C1=CC(=C(C=C1C(C(=O)O)N)O)O
https://www.w3.org/2000/01/rdf-schema#label	L-3,4-dihydroxyphenylalanine
gptkbp:isAdministeredWith	benserazide carbidopa
gptkbp:isOpticallyActive	true
gptkbp:isUsedToTreat	gptkb:Parkinson's_disease gptkb:restless_legs_syndrome dopamine-responsive dystonia
gptkbp:IUPACName	gptkb:(S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic_acid
gptkbp:meltingPoint	281°C
gptkbp:metabolism	aromatic L-amino acid decarboxylase catechol-O-methyltransferase
gptkbp:predecessor	dopamine norepinephrine epinephrine
gptkbp:PubChem_CID	gptkb:CHEBI:15765 6047
gptkbp:sells	gptkb:levodopa gptkb:Stalevo gptkb:Madopar gptkb:Parcopa gptkb:Sinemet
gptkbp:sideEffect	nausea hypotension dyskinesia
gptkbp:transportation	gptkb:large_neutral_amino_acid_transporter
gptkbp:usedAs	medication for Parkinson's disease
gptkbp:usedFor	dopaminergic therapy
gptkbp:bfsParent	gptkb:levodopa gptkb:L-DOPA
gptkbp:bfsLayer	6