|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
CD158 family
|
|
gptkbp:associatedWith
|
gptkb:cancer
infectious diseases
autoimmune diseases
|
|
gptkbp:discoveredIn
|
1990s
|
|
gptkbp:encodedBy
|
KIR genes
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
|
|
gptkbp:foundIn
|
humans
primates
|
|
gptkbp:fullName
|
Killer-cell Immunoglobulin-like Receptor family
|
|
gptkbp:function
|
regulation of immune response
recognition of HLA class I molecules
|
|
gptkbp:geneType
|
gptkb:immunoglobulin_superfamily
|
|
gptkbp:hasPolymorphism
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KIR family
|
|
gptkbp:ligand
|
gptkb:HLA-A
gptkb:HLA-B
gptkb:HLA-C
|
|
gptkbp:locatedOn
|
gptkb:chromosome_19q13.4
|
|
gptkbp:member
|
gptkb:KIR2DS1
gptkb:KIR2DL1
gptkb:KIR2DL2
gptkb:KIR2DL3
gptkb:KIR2DS2
gptkb:KIR3DL1
gptkb:KIR3DS1
KIR2DL4
KIR2DS3
KIR2DS4
KIR2DS5
KIR3DL2
KIR3DL3
|
|
gptkbp:numberOfGenes
|
15+
|
|
gptkbp:recipient
|
activating
inhibitory
|
|
gptkbp:regulates
|
cytotoxicity of NK cells
|
|
gptkbp:bfsParent
|
gptkb:Killer_cell_immunoglobulin-like_receptor_2DS1
|
|
gptkbp:bfsLayer
|
8
|