|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeTo
|
CD158b1
NKAT6
p58.2
|
|
gptkbp:associatedWith
|
infectious diseases
autoimmune diseases
|
|
gptkbp:biologicalProcess
|
immune response
MHC class I protein binding
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:contains
|
ITIM motif
|
|
gptkbp:discoveredBy
|
1990s
|
|
gptkbp:domain
|
immunoglobulin-like domain
|
|
gptkbp:encodes
|
KIR2DL2 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000277356
3803
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
some T cells
|
|
gptkbp:fullName
|
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
|
|
gptkbp:function
|
inhibitory receptor on natural killer cells
|
|
gptkbp:gene
|
gptkb:KIR2DL1
gptkb:KIR2DL3
gptkb:KIR2DS2
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:has_cytoplasmic_tail
|
long
|
|
gptkbp:hasPolymorphism
|
yes
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:6317
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KIR2DL2
|
|
gptkbp:inhibitedBy
|
NK cell activation
|
|
gptkbp:interactsWith
|
HLA-C alleles
|
|
gptkbp:length
|
370
|
|
gptkbp:locatedOnChromosome
|
19
19q13.4
|
|
gptkbp:location
|
gptkb:Leukocyte_Receptor_Complex_(LRC)
|
|
gptkbp:OMIM
|
604938
|
|
gptkbp:orthologInMouse
|
no direct ortholog
|
|
gptkbp:proteinFamily
|
killer cell immunoglobulin-like receptor
KIR gene family
|
|
gptkbp:regulates
|
cytotoxic activity of NK cells
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
P43627
|
|
gptkbp:bfsParent
|
gptkb:KIR_(killer-cell_immunoglobulin-like_receptor)
gptkb:KIR_(Killer-cell_Immunoglobulin-like_Receptor)
|
|
gptkbp:bfsLayer
|
8
|