|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:RBP2
JARID1A
|
|
gptkbp:associatedWith
|
gptkb:cancer
intellectual disability
|
|
gptkbp:biologicalProcess
|
chromatin modification
regulation of transcription
histone demethylase activity
|
|
gptkbp:domain
|
gptkb:JmjN_domain
JmjC domain
PHD finger
ARID domain
|
|
gptkbp:encodes
|
Lysine-specific demethylase 5A
|
|
gptkbp:Entrez_Gene_ID
|
5927
ENSG00000142534
|
|
gptkbp:expressedIn
|
gptkb:nucleus
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
histone demethylase
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasParalog
|
gptkb:KDM5B
KDM5C
KDM5D
|
|
gptkbp:HGNC_ID
|
HGNC:18122
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KDM5A
|
|
gptkbp:interactsWith
|
gptkb:REST
HDACs
pRB (retinoblastoma protein)
|
|
gptkbp:involvedIn
|
epigenetic regulation
transcriptional repression
|
|
gptkbp:length
|
1690
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12
|
|
gptkbp:molecularWeight
|
187 kDa
|
|
gptkbp:OMIM
|
602430
|
|
gptkbp:orthologInMouse
|
Kdm5a
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
ubiquitination
|
|
gptkbp:regulates
|
cell differentiation
gene expression
cell cycle
stem cell self-renewal
|
|
gptkbp:removesMethylGroupFrom
|
H3K4me3
H3K4me2
|
|
gptkbp:tissue_specificity
|
gptkb:testis
brain
liver
|
|
gptkbp:UniProtID
|
O75164
|
|
gptkbp:bfsParent
|
gptkb:chromosome_12p13.3
gptkb:SIN3A
gptkb:12p13.33
gptkb:chromosome_12p13.31
|
|
gptkbp:bfsLayer
|
8
|