Junctional Adhesion Molecule-A

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:cell_surface_receptor
gptkbp:alternativeName	gptkb:JAM-A gptkb:CD321
gptkbp:discoveredIn	1998
gptkbp:disulfideBond	yes
gptkbp:encodedBy	gptkb:F11R_gene
gptkbp:Entrez_Gene_ID	50848
gptkbp:expressedIn	platelets endothelial cells epithelial cells
gptkbp:foundIn	humans mice
gptkbp:function	involved in leukocyte transmigration mediates cell-cell adhesion regulates tight junction assembly
gptkbp:glycosylation	yes
gptkbp:hasCytoplasmicTail	yes
gptkbp:hasExtracellularDomain	yes
gptkbp:interactsWith	gptkb:occludin gptkb:LFA-1 ZO-1
gptkbp:involvedIn	angiogenesis inflammation tumor metastasis
gptkbp:locatedOn	cell surface
gptkbp:locatedOnChromosome	chromosome 1q21.1
gptkbp:memberOf	gptkb:immunoglobulin_superfamily
gptkbp:molecularWeight	32 kDa
gptkbp:PDB	1NBQ
gptkbp:significance	gptkb:inflammatory_bowel_disease gptkb:cancer multiple sclerosis atherosclerosis
gptkbp:transmembraneDomains	yes
gptkbp:UniProtID	gptkb:Q9Y624
gptkbp:bfsParent	gptkb:CD323
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	Junctional Adhesion Molecule-A