|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:Jmj
gptkb:JmjD2
gptkb:Jumonji
|
|
gptkbp:associatedWith
|
gptkb:Polycomb_Repressive_Complex_2
|
|
gptkbp:discoveredBy
|
1995
|
|
gptkbp:domain
|
gptkb:AT-rich_interaction_domain
Jumonji domain
|
|
gptkbp:Entrez_Gene_ID
|
3720
ENSG00000177606
|
|
gptkbp:expressedIn
|
brain
heart
embryonic stem cells
|
|
gptkbp:fullName
|
gptkb:Jumonji,_AT_Rich_Interactive_Domain_2
|
|
gptkbp:function
|
regulation of gene expression
chromatin binding
transcriptional repression
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:6180
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
JARID2
|
|
gptkbp:interactsWith
|
gptkb:EED
gptkb:EZH2
gptkb:AEBP2
gptkb:SUZ12
|
|
gptkbp:length
|
1240
|
|
gptkbp:locatedOnChromosome
|
6
6p22.3
|
|
gptkbp:molecularWeight
|
140 kDa
|
|
gptkbp:mutationAssociatedWith
|
congenital heart defects
neurodevelopmental disorders
|
|
gptkbp:OMIM
|
601594
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Jarid2
|
|
gptkbp:pathway
|
chromatin modification
epigenetic regulation
transcriptional regulation
|
|
gptkbp:regulates
|
cell differentiation
cell proliferation
cell fate determination
organ development
H3K27 methylation
PRC2 activity
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
Q92833
|
|
gptkbp:bfsParent
|
gptkb:EZH2
|
|
gptkbp:bfsLayer
|
7
|