IFIT1

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alternativeName ISG56
Interferon-stimulated gene 56
gptkbp:associatedWith gptkb:virus
gptkbp:biologicalProcess translation inhibition
RNA binding
gptkbp:discoveredIn 1986
gptkbp:domain tetratricopeptide repeat (TPR) domain
gptkbp:Entrez_Gene_ID 3434
ENSG00000119922
gptkbp:expressedIn immune cells
gptkbp:fullName Interferon-induced protein with tetratricopeptide repeats 1
gptkbp:function antiviral response
gptkbp:gene gptkb:IFIT1
gptkbp:geneType protein-coding
https://www.w3.org/2000/01/rdf-schema#label IFIT1
gptkbp:inducedBy gptkb:insulin
gptkbp:length 472 amino acids
gptkbp:locatedOnChromosome 10
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Ifit1
Ifit1b
Ifit1c
gptkbp:pathway interferon signaling pathway
gptkbp:proteinFamily IFIT family
gptkbp:regulates upregulated by viral infection
upregulated by type I interferons
gptkbp:subcellularLocation gptkb:nucleus
gptkb:cytoplasm
gptkbp:UniProtID P09914
gptkbp:bfsParent gptkb:Interferon-stimulated_gene
gptkbp:bfsLayer 7