Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
gptkb:CD275
gptkb:B7-H2 B7RP-1 LICOS |
| gptkbp:associatedWith |
autoimmune diseases
immunodeficiency |
| gptkbp:binds |
gptkb:ICOS
|
| gptkbp:biologicalProcess |
immune response
receptor binding regulation of cytokine production T cell costimulation |
| gptkbp:cellularComponent |
gptkb:plasma_membrane
|
| gptkbp:discoveredBy |
1999
|
| gptkbp:encodedBy |
ICOSLG gene
|
| gptkbp:Entrez_Gene_ID |
23308
|
| gptkbp:expressedIn |
gptkb:B_cells
dendritic cells macrophages monocytes antigen-presenting cells |
| gptkbp:fullName |
Inducible T-cell co-stimulator ligand
|
| gptkbp:function |
costimulatory molecule for T cell activation
|
| gptkbp:HGNC_ID |
HGNC:19100
|
| https://www.w3.org/2000/01/rdf-schema#label |
ICOSL
|
| gptkbp:locatedOnChromosome |
chromosome 21
|
| gptkbp:OMIM |
604558
|
| gptkbp:pathway |
gptkb:T_cell_receptor_signaling_pathway
costimulatory signaling pathway |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
O75144
|
| gptkbp:bfsParent |
gptkb:CD278
|
| gptkbp:bfsLayer |
8
|