Human Leukocyte Antigen genes

URI: https://gptkb.org/entity/Human_Leukocyte_Antigen_genes
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:HLA_genes
gptkbp:associatedWith autoimmune diseases
gptkbp:database IMGT/HLA database
gptkbp:discoveredBy gptkb:Jean_Dausset
gptkbp:encodes major histocompatibility complex proteins
gptkbp:firstDescribed 1958
gptkbp:function immune system regulation
gptkbp:hasPolymorphism true
gptkbp:HLA_class_I_genes gptkb:HLA-A
gptkb:HLA-B
gptkb:HLA-C
gptkbp:HLA_class_II_genes gptkb:HLA-DP
gptkb:HLA-DQ
gptkb:HLA-DR
gptkbp:HLA_class_III_genes cytokines
complement proteins
https://www.w3.org/2000/01/rdf-schema#label Human Leukocyte Antigen genes
gptkbp:importantFor organ transplantation compatibility
gptkbp:involvedIn antigen presentation
gptkbp:locatedOn gptkb:chromosome_6
gptkbp:orthologIn MHC genes in other vertebrates
gptkbp:species gptkb:Homo_sapiens
gptkbp:subclassOf gptkb:HLA_class_III_genes
gptkb:HLA_class_II_genes
gptkb:HLA_class_I_genes
gptkbp:usedIn population genetics
paternity testing
disease association studies
gptkbp:bfsParent gptkb:HLA_genes
gptkbp:bfsLayer 7