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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alsoKnownAs
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gptkb:Heat_shock_protein_40
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gptkbp:associatedWith
|
protein misfolding diseases
|
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gptkbp:discoveredIn
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gptkb:Bacteria
|
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gptkbp:domain
|
J-domain
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gptkbp:example
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gptkb:DNAJA1
gptkb:DNAJB1
DNAJC7
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gptkbp:foundIn
|
prokaryotes
eukaryotes
|
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gptkbp:function
|
protein binding
molecular chaperone
chaperone binding
prevents protein aggregation
assists protein folding
|
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gptkbp:GOProcess
|
protein refolding
response to heat
|
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https://www.w3.org/2000/01/rdf-schema#label
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Hsp40
|
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gptkbp:interactsWith
|
gptkb:Hsp70
|
|
gptkbp:namedAfter
|
40 kDa molecular weight
|
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gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Homo_sapiens
gptkb:Drosophila_melanogaster
|
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gptkbp:proteinFamily
|
gptkb:DNAJ
|
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gptkbp:regulates
|
Hsp70 ATPase activity
|
|
gptkbp:role
|
cellular stress response
protein homeostasis
|
|
gptkbp:structure
|
C-terminal domain
G/F-rich region
J-domain at N-terminus
|
|
gptkbp:subfamily
|
gptkb:DNAJA
gptkb:DNAJB
gptkb:DNAJC
|
|
gptkbp:UniProtID
|
Chaperone
|
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gptkbp:bfsParent
|
gptkb:Hsp70
|
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gptkbp:bfsLayer
|
7
|