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gptkbp:instanceOf
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gptkb:gene
|
|
gptkbp:alias
|
gptkb:HSP70-1
gptkb:HSP70-1A
HSP70A
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
autoimmune diseases
heat shock response
|
|
gptkbp:biologicalProcess
|
ATP binding
response to stress
protein refolding
unfolded protein binding
response to heat
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
mitochondrion
|
|
gptkbp:conservedIn
|
mammals
vertebrates
|
|
gptkbp:discoveredBy
|
1980s
|
|
gptkbp:encodes
|
gptkb:Heat_shock_70_kDa_protein_1A
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000204388
3303
|
|
gptkbp:expressedIn
|
various tissues
cellular stress
|
|
gptkbp:function
|
protein folding
cellular stress response
chaperone activity
|
|
gptkbp:GOID
|
GO:0006457
GO:0006986
|
|
gptkbp:hasParalog
|
gptkb:HSPA1B_gene
gptkb:HSPA1L_gene
|
|
gptkbp:hasTranscriptVariant
|
1 known variant
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:5232
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HSPA1A gene
|
|
gptkbp:length
|
641 amino acids
2,142 base pairs
|
|
gptkbp:locatedInCytogeneticBand
|
6p21.33
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:memberOf
|
gptkb:HSP70_family
|
|
gptkbp:OMIM
|
140550
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Hspa1a
|
|
gptkbp:product
|
Hsp70-1A
|
|
gptkbp:proteinFamily
|
ATPase domain
substrate-binding domain
|
|
gptkbp:regulates
|
induced by oxidative stress
induced by heat shock
|
|
gptkbp:UniProtID
|
gptkb:P0DMV8
|
|
gptkbp:bfsParent
|
gptkb:6p21.3
|
|
gptkbp:bfsLayer
|
7
|