HMGB proteins

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alias gptkb:amphoterin
HMG-1 proteins
gptkbp:binds bent DNA
non-B DNA structures
gptkbp:conservedIn HMG-box domain
gptkbp:discoveredBy Alan P. Wolffe
gptkbp:extracellularFunction cytokine activity
gptkbp:fullName High Mobility Group Box proteins
gptkbp:function regulation of transcription
DNA binding
chromatin remodeling
https://www.w3.org/2000/01/rdf-schema#label HMGB proteins
gptkbp:location gptkb:nucleus
gptkbp:member gptkb:HMGB1
HMGB2
HMGB3
HMGB4
gptkbp:organism eukaryotes
gptkbp:postTranslationalModification phosphorylation
methylation
acetylation
gptkbp:proteinFamily HMG gene family
gptkbp:relatedTo gptkb:HMGA_proteins
gptkb:HMGN_proteins
gptkbp:role gptkb:cancer
apoptosis
cell differentiation
DNA repair
autoimmune diseases
inflammation
gptkbp:bfsParent gptkb:high-mobility_group_proteins
gptkbp:bfsLayer 8