high-mobility group proteins
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:HMG_proteins
|
| gptkbp:associatedWith |
autoimmune diseases
inflammation metastasis |
| gptkbp:binds |
minor groove of DNA
|
| gptkbp:contains |
HMG-box domain
|
| gptkbp:discoveredBy |
gptkb:Lennart_Philipson
|
| gptkbp:firstDescribed |
1973
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
bind DNA
regulate transcription |
| https://www.w3.org/2000/01/rdf-schema#label |
high-mobility group proteins
|
| gptkbp:interactsWith |
gptkb:nucleosomes
transcription factors |
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:member |
gptkb:HMGA_proteins
gptkb:HMGB_proteins gptkb:HMGN_proteins |
| gptkbp:molecularWeight |
10-30 kDa
|
| gptkbp:role |
cell differentiation
DNA repair cancer progression gene expression regulation chromatin remodeling |
| gptkbp:structure |
contain AT-hook or HMG-box motifs
|
| gptkbp:subclassOf |
gptkb:non-histone_chromosomal_proteins
|
| gptkbp:bfsParent |
gptkb:HMG_box
|
| gptkbp:bfsLayer |
7
|