Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
HMG-I/Y proteins
architectural transcription factors |
| gptkbp:amendedBy |
phosphorylation
methylation acetylation |
| gptkbp:associatedWith |
gptkb:cancer
benign tumors |
| gptkbp:contains |
AT-hook DNA binding motifs
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
HMGA2 gene
HMGA1 gene |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
High Mobility Group A proteins
|
| gptkbp:function |
regulation of transcription
DNA binding chromatin remodeling |
| https://www.w3.org/2000/01/rdf-schema#label |
HMGA proteins
|
| gptkbp:interactsWith |
transcription factors
chromatin remodeling complexes |
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:member |
HMGA2
HMGA1 |
| gptkbp:overexpressedIn |
malignant transformation
|
| gptkbp:regulates |
gene expression
|
| gptkbp:role |
differentiation
cell growth neoplastic transformation |
| gptkbp:structure |
gptkb:non-histone_chromosomal_proteins
|
| gptkbp:usedAs |
biomarker in cancer research
|
| gptkbp:bfsParent |
gptkb:high-mobility_group_proteins
|
| gptkbp:bfsLayer |
8
|