|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:HDR_syndrome_gene
gptkb:GATA-3
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:hypoparathyroidism
gptkb:Barakat_syndrome
|
|
gptkbp:discoveredBy
|
gptkb:Stuart_H._Orkin
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:DNA_binding_domain
|
zinc finger
|
|
gptkbp:Entrez_Gene_ID
|
2625
ENSG00000107485
|
|
gptkbp:expressedIn
|
gptkb:kidney
central nervous system
parathyroid gland
T lymphocytes
|
|
gptkbp:fullName
|
gptkb:GATA_binding_protein_3
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0005634
GO:0003700
GO:0006355
|
|
gptkbp:HGNC_ID
|
HGNC:4171
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Gata3
|
|
gptkbp:involvedIn
|
cell differentiation
embryonic development
immune system regulation
T-cell development
|
|
gptkbp:length
|
444 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10
|
|
gptkbp:location
|
gptkb:10p14
|
|
gptkbp:molecularWeight
|
48 kDa
|
|
gptkbp:mutationAssociatedWith
|
developmental disorders
immunodeficiency
|
|
gptkbp:OMIM
|
131320
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Gata3
zebrafish gata3
|
|
gptkbp:proteinFamily
|
gptkb:GATA_family
|
|
gptkbp:RefSeq
|
NM_002051
|
|
gptkbp:regulates
|
Th2 cell differentiation
IL-13 expression
IL-4 expression
IL-5 expression
|
|
gptkbp:transcriptionRegulatorOf
|
T-bet
Foxp3
Runx3
|
|
gptkbp:UniProtID
|
gptkb:P23771
|
|
gptkbp:bfsParent
|
gptkb:chromosome_7_(mouse)
gptkb:GATA3
gptkb:ENSG00000111331
|
|
gptkbp:bfsLayer
|
7
|