|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:GATA3
gptkb:GATA-3
HDR syndrome protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:hypoparathyroidism
|
|
gptkbp:biologicalProcess
|
transcription regulation
DNA binding
|
|
gptkbp:discoveredBy
|
1990s
|
|
gptkbp:domain
|
GATA-type zinc finger
|
|
gptkbp:encodedBy
|
gptkb:GATA3_gene
|
|
gptkbp:Entrez_Gene_ID
|
2625
ENSG00000107485
|
|
gptkbp:expressedIn
|
parathyroid gland
immune system
breast tissue
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:gene
|
gptkb:GATA3
|
|
gptkbp:HGNC_ID
|
4171
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GATA binding protein 3
|
|
gptkbp:length
|
444
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10
|
|
gptkbp:molecularWeight
|
48 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:HDR_syndrome
gptkb:Barakat_syndrome
|
|
gptkbp:OMIM
|
131320
|
|
gptkbp:orthologInMouse
|
gptkb:Gata3
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
acetylation
|
|
gptkbp:proteinFamily
|
gptkb:GATA_family
|
|
gptkbp:regulates
|
T-cell development
Th2 cell differentiation
epithelial cell differentiation
development of auditory system
development of kidneys
development of parathyroid glands
gene expression in immune response
interleukin-13 expression
interleukin-4 expression
interleukin-5 expression
urothelial cell differentiation
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:P23771
|
|
gptkbp:used_as_marker_for
|
gptkb:urothelial_carcinoma
breast carcinoma
parathyroid tumors
|
|
gptkbp:bfsParent
|
gptkb:GATA3
gptkb:ENSG00000113721
|
|
gptkbp:bfsLayer
|
7
|