Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
ABC transporter |
| gptkbp:activatedBy |
gptkb:insulin
|
| gptkbp:alternativeName |
gptkb:Solute_carrier_family_2,_facilitated_glucose_transporter_member_4
|
| gptkbp:discoveredIn |
1988
|
| gptkbp:encodedBy |
gptkb:SLC2A4_gene
|
| gptkbp:foundIn |
gptkb:skeletal_muscle
cardiac muscle adipose tissue |
| gptkbp:function |
facilitated glucose transport
|
| https://www.w3.org/2000/01/rdf-schema#label |
GLUT4 protein
|
| gptkbp:location |
intracellular vesicles
|
| gptkbp:memberOf |
gptkb:GLUT_family
|
| gptkbp:molecularWeight |
approximately 55 kDa
|
| gptkbp:regulates |
upregulated by exercise
downregulated in type 2 diabetes |
| gptkbp:relatedTo |
gptkb:metabolic_syndrome
obesity insulin resistance glucose homeostasis |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:structure |
12 transmembrane domains
|
| gptkbp:translocatesTo |
gptkb:plasma_membrane
|
| gptkbp:UniProtID |
gptkb:P14672
|
| gptkbp:bfsParent |
gptkb:ENSG00000120948
|
| gptkbp:bfsLayer |
6
|