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gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:SLC2A_family
|
|
gptkbp:database
|
gptkb:InterPro:_IPR005828
gptkb:Pfam:_PF00083
HGNC:11005 (SLC2A1)
UniProt: P11166 (GLUT1)
|
|
gptkbp:encodedBy
|
gptkb:SLC2A_genes
|
|
gptkbp:firstDescribed
|
1980s
|
|
gptkbp:foundIn
|
animals
humans
fungi
plants
|
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gptkbp:fullName
|
gptkb:Glucose_transporter_family
|
|
gptkbp:function
|
facilitate glucose transport across cell membranes
|
|
gptkbp:hasMember
|
gptkb:GLUT4
gptkb:GLUT1
gptkb:GLUT9
gptkb:GLUT2
gptkb:GLUT3
gptkb:GLUT10
gptkb:GLUT11
gptkb:GLUT12
gptkb:GLUT13
gptkb:GLUT5
gptkb:GLUT6
gptkb:GLUT7
gptkb:GLUT8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GLUT family
|
|
gptkbp:locale
|
gptkb:cell_membrane
intracellular vesicles
|
|
gptkbp:mechanismOfAction
|
facilitated diffusion
|
|
gptkbp:memberOf
|
gptkb:solute_carrier_family
|
|
gptkbp:numberOfMembers
|
14
|
|
gptkbp:proteinFamily
|
gptkb:SLC2
|
|
gptkbp:relatedTo
|
gptkb:diabetes_mellitus
glucose homeostasis
insulin response
|
|
gptkbp:significance
|
gptkb:GLUT1_deficiency_syndrome
GLUT2 mutations cause Fanconi-Bickel syndrome
GLUT4 involved in insulin resistance
|
|
gptkbp:transportedMolecule
|
gptkb:dehydroascorbic_acid
glucose
fructose
galactose
|
|
gptkbp:bfsParent
|
gptkb:GLUT3_transporter
gptkb:GLUT4_transporter
gptkb:GLUT-4
gptkb:GLUT4_protein
|
|
gptkbp:bfsLayer
|
7
|