|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:discoveredBy
|
gptkb:Yamamoto_et_al.
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:domain
|
zinc finger
|
|
gptkbp:encodedBy
|
GATA4 gene
|
|
gptkbp:Entrez_Gene_ID
|
2626
ENSG00000136574
|
|
gptkbp:expressedIn
|
heart
liver
intestine
gonads
|
|
gptkbp:fullName
|
GATA binding protein 4
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
4173
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GATA4
|
|
gptkbp:interactsWith
|
gptkb:NKX2-5
gptkb:TBX5
FOG2
|
|
gptkbp:locatedOnChromosome
|
8p23.1
|
|
gptkbp:molecularWeight
|
44 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:atrial_septal_defect
gptkb:ventricular_septal_defect
congenital heart defects
gonadal dysgenesis
|
|
gptkbp:OMIM
|
600576
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Gata4
|
|
gptkbp:phosphorylates
|
gptkb:MAPK
gptkb:PKC
PKA
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
cell survival
angiogenesis
cardiac development
gonadal development
lung development
sex differentiation
pancreas development
ANF gene
BNP gene
cardiac muscle gene expression
endodermal development
intestinal development
liver development
ventricular morphogenesis
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
P43694
|
|
gptkbp:bfsParent
|
gptkb:Familial_atrial_fibrillation
gptkb:MEF2C
gptkb:NKX2-5
gptkb:chromosome_8_(human)
|
|
gptkbp:bfsLayer
|
7
|