|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:FZD2
Fz-2
|
|
gptkbp:associatedWith
|
developmental processes
|
|
gptkbp:cellularComponent
|
gptkb:cell_membrane
|
|
gptkbp:domain
|
seven-transmembrane domain
|
|
gptkbp:encodedBy
|
FZD2 gene
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
gptkb:Wnt_signaling_receptor
|
|
gptkbp:hasExtracellularDomain
|
cysteine-rich domain
|
|
gptkbp:hasIntracellularDomain
|
C-terminal tail
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Frizzled-2
|
|
gptkbp:involvedIn
|
cell differentiation
cell proliferation
embryonic development
cell signaling
|
|
gptkbp:ligand
|
gptkb:Wnt5a
gptkb:Wnt7b
gptkb:Wnt3a
|
|
gptkbp:locatedOnChromosome
|
chromosome 17q21.1
|
|
gptkbp:memberOf
|
frizzled family
|
|
gptkbp:molecularWeight
|
~65 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Robinow_syndrome
autosomal dominant omodysplasia
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
|
|
gptkbp:pathway
|
non-canonical Wnt signaling pathway
canonical Wnt signaling pathway
|
|
gptkbp:receptorFor
|
gptkb:Wnt_proteins
|
|
gptkbp:transmembraneDomains
|
yes
|
|
gptkbp:UniProtID
|
Q14332
|
|
gptkbp:bfsParent
|
gptkb:FZD2
gptkb:Frizzled_family
gptkb:Wnt5a
gptkb:Family:_Frizzled
gptkb:Frizzled_family_receptors
|
|
gptkbp:bfsLayer
|
8
|