Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
blood coagulation factor |
| gptkbp:binds |
gptkb:Factor_Xa
calcium ions phospholipid membranes |
| gptkbp:cleaved_by |
gptkb:thrombin
|
| gptkbp:deficiencyCauses |
bleeding disorders
|
| gptkbp:encodedBy |
F5 gene
|
| gptkbp:Factor_V_Leiden_mutation_causes |
resistance to activated protein C
|
| gptkbp:function |
cofactor in prothrombinase complex
|
| gptkbp:halfLife |
short (minutes)
|
| https://www.w3.org/2000/01/rdf-schema#label |
Factor Va
|
| gptkbp:inhibitedBy |
protein S
activated protein C |
| gptkbp:is_activated_form_of |
Factor V
|
| gptkbp:location |
gptkb:plasma
|
| gptkbp:molecularWeight |
~330 kDa
|
| gptkbp:mutationAssociatedWith |
Factor V Leiden
|
| gptkbp:promotes_conversion_of |
prothrombin to thrombin
|
| gptkbp:role |
blood coagulation
|
| gptkbp:structure |
heterodimer of heavy and light chains
|
| gptkbp:bfsParent |
gptkb:Factor_Xa
|
| gptkbp:bfsLayer |
7
|