Statements (19)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeSplicingVariants |
Type 1 fusion
Type 2 fusion |
| gptkbp:associatedWith |
gptkb:Ewing_sarcoma
|
| gptkbp:cause |
oncogenic transformation
|
| gptkbp:chromosomalTranslocation |
gptkb:t(11;22)(q24;q12)
|
| gptkbp:detects |
gptkb:FISH
gptkb:RT-PCR |
| gptkbp:discoveredIn |
1992
|
| gptkbp:encodes |
abnormal transcription factor
|
| https://www.w3.org/2000/01/rdf-schema#label |
EWSR1-FLI1 fusion gene
|
| gptkbp:mergedInto |
EWSR1 gene
FLI1 gene |
| gptkbp:presentIn |
majority of Ewing sarcoma cases
|
| gptkbp:regulates |
gene expression
|
| gptkbp:target |
molecular targeted therapy
|
| gptkbp:usedAs |
diagnostic marker
|
| gptkbp:bfsParent |
gptkb:Ewing_sarcoma
|
| gptkbp:bfsLayer |
6
|