|
gptkbp:instanceOf
|
gptkb:cancer
gptkb:disease
gptkb:rhabdomyosarcoma
|
|
gptkbp:affects
|
gptkb:bone
soft tissue
|
|
gptkbp:commonIn
|
adolescents
children
|
|
gptkbp:firstDescribed
|
gptkb:James_Ewing
1921
|
|
gptkbp:hasGeneticAlteration
|
gptkb:EWSR1-FLI1_fusion_gene
t(11;22)(q24;q12) translocation
|
|
gptkbp:hasImmunohistochemistryMarker
|
CD99 positive
FLI1 positive
|
|
gptkbp:hasMetastasisSite
|
lungs
bone marrow
other bones
|
|
gptkbp:hasOrphanetID
|
287
|
|
gptkbp:hasSurvivalRate
|
about 30% (metastatic disease)
about 70% (localized disease)
|
|
gptkbp:histology
|
small round blue cells
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ewing tumor
|
|
gptkbp:ICD-10_code
|
C40
C41
|
|
gptkbp:location
|
gptkb:meat
femur
pelvis
long bones
|
|
gptkbp:MeSH_ID
|
D013545
|
|
gptkbp:OMIM
|
612219
|
|
gptkbp:partOf
|
gptkb:Ewing_family_of_tumors
|
|
gptkbp:prognosis
|
variable
|
|
gptkbp:rarity
|
true
|
|
gptkbp:riskFactor
|
male sex
Caucasian ethnicity
age (children, adolescents)
|
|
gptkbp:stageName
|
gptkb:AJCC_system
gptkb:Enneking_system
|
|
gptkbp:symptom
|
fever
pain
weight loss
swelling
|
|
gptkbp:synonym
|
gptkb:Ewing's_sarcoma
gptkb:Ewing_sarcoma
|
|
gptkbp:treatment
|
surgery
radiation therapy
chemotherapy
|
|
gptkbp:bfsParent
|
gptkb:Ewing_sarcoma
|
|
gptkbp:bfsLayer
|
6
|