Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:T-cell_acute_lymphocytic_leukemia_protein_1
SCL protein |
| gptkbp:associatedWith |
gptkb:T-cell_acute_lymphoblastic_leukemia
|
| gptkbp:binds |
E-box DNA sequences
|
| gptkbp:discoveredIn |
1990
|
| gptkbp:domain |
basic helix-loop-helix domain
|
| gptkbp:encodedBy |
TAL1 gene
|
| gptkbp:expressedIn |
hematopoietic stem cells
erythroid cells |
| gptkbp:formsComplexWith |
gptkb:E2A_protein
gptkb:GATA1_protein LDB1 protein LDB2 protein LMO2 protein Lyl1 protein |
| gptkbp:function |
transcription factor
|
| gptkbp:HGNC_ID |
11556
|
| https://www.w3.org/2000/01/rdf-schema#label |
TAL1 protein
|
| gptkbp:involvedIn |
erythropoiesis
hematopoiesis |
| gptkbp:locatedOnChromosome |
gptkb:1p32
|
| gptkbp:molecularWeight |
34 kDa
|
| gptkbp:mutationAssociatedWith |
leukemogenesis
|
| gptkbp:orthologInMouse |
Tal1 protein
|
| gptkbp:regulates |
cell differentiation
cell proliferation gene expression |
| gptkbp:subcellularLocation |
gptkb:nucleus
|
| gptkbp:UniProtID |
P17542
|
| gptkbp:bfsParent |
gptkb:TAL1
|
| gptkbp:bfsLayer |
7
|