Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
vasoconstrictor
peptide |
| gptkbp:aminoAcidLength |
21
|
| gptkbp:category |
vasoactive peptide
human protein endothelin family |
| gptkbp:discoveredBy |
Masashi Yanagisawa
|
| gptkbp:discoveredIn |
1988
|
| gptkbp:encodedBy |
gptkb:EDN1_gene
|
| gptkbp:foundIn |
endothelial cells
|
| gptkbp:function |
cell proliferation
vasoconstriction hormone activity regulation of vascular tone |
| gptkbp:HGNC_ID |
3176
|
| https://www.w3.org/2000/01/rdf-schema#label |
Endothelin-1
|
| gptkbp:inhibitedBy |
gptkb:bosentan
ambrisentan macitentan |
| gptkbp:locatedOnChromosome |
6p24.1
|
| gptkbp:predecessor |
preproendothelin-1
|
| gptkbp:recipient |
gptkb:endothelin_receptor_type_A
gptkb:endothelin_receptor_type_B |
| gptkbp:relatedTo |
gptkb:cancer
heart failure kidney disease atherosclerosis hypertension pulmonary arterial hypertension |
| gptkbp:structure |
21-amino acid peptide
|
| gptkbp:UniProtID |
P05305
|
| gptkbp:bfsParent |
gptkb:ET-1
|
| gptkbp:bfsLayer |
7
|