Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:alternativeName |
gptkb:EDNRB
ETB receptor |
| gptkbp:associatedWith |
gptkb:Hirschsprung's_disease
|
| gptkbp:binds |
gptkb:endothelin-1
endothelin-2 endothelin-3 |
| gptkbp:biologicalProcess |
G-protein coupled receptor activity
|
| gptkbp:cellularComponent |
gptkb:plasma_membrane
|
| gptkbp:encodedBy |
gptkb:EDNRB_gene
|
| gptkbp:expressedIn |
endothelial cells
neuronal cells |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
neural crest cell development
regulation of vascular tone clearance of endothelins |
| gptkbp:HGNC_ID |
3173
|
| https://www.w3.org/2000/01/rdf-schema#label |
endothelin receptor type B
|
| gptkbp:locatedOn |
chromosome 13q22
|
| gptkbp:OMIM |
131244
|
| gptkbp:role |
vasodilation
melanocyte development |
| gptkbp:type |
gptkb:Gi/o_protein_pathway
Gq/11 protein pathway |
| gptkbp:UniProtID |
P24530
|
| gptkbp:bfsParent |
gptkb:ET-1
|
| gptkbp:bfsLayer |
7
|