|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:ET-1
gptkb:ET1
PPET1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cardiovascular_disease
hypertension
pulmonary arterial hypertension
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:encodes
|
endothelin-1 protein
|
|
gptkbp:Entrez_Gene_ID
|
1906
ENSG00000151617
|
|
gptkbp:expressedIn
|
endothelial cells
|
|
gptkbp:fullName
|
endothelin 1
|
|
gptkbp:function
|
regulation of blood pressure
vasoconstriction
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
3176
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
6p24.1
|
|
gptkbp:mutationAssociatedWith
|
can cause vascular disorders
|
|
gptkbp:OMIM
|
131240
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Edn1
|
|
gptkbp:pathway
|
G protein-coupled receptor signaling pathway
endothelin signaling pathway
|
|
gptkbp:product
|
gptkb:endothelin-1
preproendothelin-1
|
|
gptkbp:regulates
|
vascular tone
|
|
gptkbp:UniProtID
|
P05305
|
|
gptkbp:bfsParent
|
gptkb:ET-1
gptkb:endothelin-1
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
EDN1 gene
|