Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:ET-1
gptkb:ET1 PPET1 |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cardiovascular_disease
hypertension pulmonary arterial hypertension |
| gptkbp:discoveredIn |
1988
|
| gptkbp:encodes |
endothelin-1 protein
|
| gptkbp:Entrez_Gene_ID |
1906
ENSG00000151617 |
| gptkbp:expressedIn |
endothelial cells
|
| gptkbp:fullName |
endothelin 1
|
| gptkbp:function |
regulation of blood pressure
vasoconstriction |
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
3176
|
| https://www.w3.org/2000/01/rdf-schema#label |
EDN1 gene
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_6
6p24.1 |
| gptkbp:mutationAssociatedWith |
can cause vascular disorders
|
| gptkbp:OMIM |
131240
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Edn1
|
| gptkbp:pathway |
G protein-coupled receptor signaling pathway
endothelin signaling pathway |
| gptkbp:product |
gptkb:endothelin-1
preproendothelin-1 |
| gptkbp:regulates |
vascular tone
|
| gptkbp:UniProtID |
P05305
|
| gptkbp:bfsParent |
gptkb:ET-1
|
| gptkbp:bfsLayer |
7
|