Statements (24)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alsoKnownAs |
gptkb:F-box_protein_5
|
gptkbp:associatedWith |
cancer progression
|
gptkbp:degradedBy |
gptkb:SCF_ubiquitin_ligase_complex
|
gptkbp:discoveredIn |
2001
|
gptkbp:domain |
F-box domain
Zinc-binding domain |
gptkbp:encodedBy |
gptkb:FBXO5_gene
|
gptkbp:expressedIn |
various human tissues
|
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:function |
inhibitor of the anaphase-promoting complex/cyclosome (APC/C)
|
https://www.w3.org/2000/01/rdf-schema#label |
Emi1
|
gptkbp:inhibitedBy |
ubiquitin ligase activity of APC/C
|
gptkbp:involvedIn |
mitotic progression
|
gptkbp:locale |
gptkb:nucleus
|
gptkbp:orthologIn |
gptkb:Danio_rerio
gptkb:Mus_musculus |
gptkbp:phosphorylates |
gptkb:Polo-like_kinase_1_(PLK1)
|
gptkbp:regulates |
cell cycle
S phase entry |
gptkbp:UniProtID |
gptkb:Q9UKT4
|
gptkbp:bfsParent |
gptkb:Anaphase-Promoting_Complex
gptkb:APC_complex |
gptkbp:bfsLayer |
6
|