SCF ubiquitin ligase complex
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
SCF complex
Skp1-Cullin-F-box complex |
| gptkbp:amendedBy |
target proteins with ubiquitin
|
| gptkbp:discoveredBy |
gptkb:Raymond_Deshaies
|
| gptkbp:discoveredIn |
1996
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
ubiquitin ligase activity
|
| gptkbp:GO_term |
GO:0019005
|
| gptkbp:hasComponent |
F-box protein
Cullin1 Rbx1 Skp1 |
| https://www.w3.org/2000/01/rdf-schema#label |
SCF ubiquitin ligase complex
|
| gptkbp:involvedIn |
protein degradation
ubiquitination |
| gptkbp:regulates |
signal transduction
transcription cell cycle |
| gptkbp:relatedTo |
proteasome pathway
|
| gptkbp:requires |
gptkb:ATP
gptkb:E2_ubiquitin-conjugating_enzyme |
| gptkbp:substrateRecognitionBy |
F-box protein
|
| gptkbp:target |
phosphorylated proteins
|
| gptkbp:type |
E3 ubiquitin ligase
|
| gptkbp:bfsParent |
gptkb:Emi1
|
| gptkbp:bfsLayer |
7
|