|
gptkbp:instanceOf
|
gptkb:receptor_tyrosine_kinase
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:EphA1
gptkb:EPHT
Eph-like receptor tyrosine kinase
Epithelial cell kinase
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
colorectal cancer
|
|
gptkbp:biologicalProcess
|
immune response
nervous system development
protein tyrosine kinase activity
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
Nobumasa Takahashi
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodedBy
|
EPHA1 gene
|
|
gptkbp:Entrez_Gene_ID
|
2041
ENSG00000146904
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
liver
colon
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
cell migration
cell signaling
cell adhesion
axon guidance
|
|
gptkbp:HGNC_ID
|
gptkb:EPHA1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
EPH receptor A1
|
|
gptkbp:ligand
|
ephrin-A1
ephrin-A4
|
|
gptkbp:locatedOnChromosome
|
chromosome 7q34
|
|
gptkbp:memberOf
|
EPH receptor family
Ephrin receptor subfamily
|
|
gptkbp:OMIM
|
179610
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
1MQB
|
|
gptkbp:phosphorylates
|
tyrosine residue
|
|
gptkbp:RefSeq
|
NM_005232
|
|
gptkbp:type
|
gptkb:MAPK_pathway
gptkb:PI3K/AKT_pathway
|
|
gptkbp:UniProtID
|
P21709
|
|
gptkbp:bfsParent
|
gptkb:EPHA1
|
|
gptkbp:bfsLayer
|
8
|