|
gptkbp:instanceOf
|
Ensembl gene ID
|
|
gptkbp:alternativeName
|
gptkb:S-mephenytoin_4-hydroxylase
gptkb:cytochrome_P450_family_2_subfamily_C_member_19
|
|
gptkbp:associatedWith
|
pharmacogenomics
adverse drug reactions
omeprazole metabolism
clopidogrel response
|
|
gptkbp:encodes
|
gptkb:CYP2C19
|
|
gptkbp:Entrez_Gene_ID
|
1557
|
|
gptkbp:enzymeCommissionNumber
|
gptkb:EC_1.14.13.13
|
|
gptkbp:expressedIn
|
gptkb:small_intestine
brain
liver
|
|
gptkbp:gene
|
gptkb:CYP2C19
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPolymorphism
|
gptkb:CYP2C19*17
gptkb:CYP2C19*2
gptkb:CYP2C19*3
|
|
gptkbp:hasRefSeqID
|
NM_000769
|
|
gptkbp:HGNC_ID
|
HGNC:2621
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ENSG00000115275
|
|
gptkbp:involvedIn
|
drug metabolism
xenobiotic metabolism
|
|
gptkbp:isMemberOfGeneFamily
|
gptkb:cytochrome_P450
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10
|
|
gptkbp:OMIM
|
124020
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
Drug metabolism - cytochrome P450
Metabolism of xenobiotics by cytochrome P450
Arachidonic acid metabolism
|
|
gptkbp:PDB
|
4GQS
4GQA
4GQB
4GQC
4GQD
4GQE
4GQF
4GQG
4GQH
4GQI
4GQJ
4GQK
4GQL
4GQM
4GQN
4GQO
4GQP
4GQQ
4GQR
4GQT
4GQU
4GQV
4GQW
4GQX
4GQY
4GQZ
|
|
gptkbp:significance
|
poor metabolizer phenotype
ultrarapid metabolizer phenotype
|
|
gptkbp:startPoint
|
94761948
94842860
|
|
gptkbp:strand
|
plus
|
|
gptkbp:UniProtID
|
gptkb:P33261
|
|
gptkbp:bfsParent
|
gptkb:ATP-binding_cassette_sub-family_B_member_2
|
|
gptkbp:bfsLayer
|
8
|