E6-AP ubiquitin-protein ligase
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:E6-associated_protein
UBE3A protein |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:Angelman_syndrome |
| gptkbp:biologicalProcess |
protein ubiquitination
proteasomal protein catabolic process |
| gptkbp:discoveredBy |
Huibregtse JM
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
gptkb:UBE3A_gene
|
| gptkbp:function |
E3 ubiquitin ligase
ubiquitin-protein ligase activity |
| https://www.w3.org/2000/01/rdf-schema#label |
E6-AP ubiquitin-protein ligase
|
| gptkbp:interactsWith |
gptkb:HPV_E6_protein
|
| gptkbp:locatedOnChromosome |
gptkb:15q11-q13
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
~100 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:Angelman_syndrome
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
gptkb:Q05086
|
| gptkbp:bfsParent |
gptkb:Ube3a
|
| gptkbp:bfsLayer |
8
|