Gemin6

E561088

Gemin6 is a component of the SMN (survival motor neuron) complex involved in the assembly and maturation of small nuclear ribonucleoproteins essential for pre-mRNA splicing.

All labels observed (5)

Label Occurrences
Gemin6 canonical 7
Gemin proteins 2
GEMIN6 gene 1

How this entity was disambiguated

Statements (43)

Predicate Object
instanceOf SMN complex component
protein
protein-coding gene
associatedWith SMN complex
motor neuron function
spinal muscular atrophy pathway
binds Gemin7
SMN1 protein
linked to: SMN1 gene
biologicalProcess RNA splicing
U snRNP assembly
mRNA processing
cellularComponent SMN complex
cytoplasmic ribonucleoprotein granule
nuclear body
conservedIn metazoans
vertebrates
encodedBy GEMIN6 gene
linked to: Gemin6
encodes Gemin6
expressedIn human cells
neuronal tissue
formsComplexWith Gemin2
Gemin3
Gemin4
Gemin5
Gemin7
SMN1 protein
linked to: SMN1 gene
involvedIn spliceosome biogenesis
locatedIn Cajal bodies
Gems
cytoplasm
nucleus
locatedOn human chromosome 2
molecularFunction RNA binding
protein binding
orthologOf mouse Gemin6
zebrafish Gemin6
linked to: Gemin6
participatesIn pre-mRNA splicing
small nuclear ribonucleoprotein assembly
snRNP maturation
partOf SMN complex
requiredFor efficient snRNP assembly
proper spliceosome function
taxon Homo sapiens

How these facts were elicited

Referenced by (12)

Full triples — surface form annotated when it differs from this entity's canonical label.

Survival motor neuron protein formsComplexWith Gemin6
subject linked to: survival motor neuron protein
gems (Gemini of Cajal bodies) contains Gemin proteins
linked to: Gemin6
Gemin4 inComplexWith Gemin6
Gemin5 interactsWith Gemin6
Gemin6 orthologOf zebrafish Gemin6
linked to: Gemin6
Gemin6 encodedBy GEMIN6 gene
linked to: Gemin6
GEMIN6 gene encodes Gemin6
subject linked to: Gemin6
Gemin8 binds Gemin6
Gemin8 associatedWithComplex Gemin6–Gemin7–Gemin8 subcomplex
linked to: Gemin6
Sm proteins interactsWith Gemin proteins
linked to: Gemin6
SMN complex hasComponent Gemin6